Suspected covert lorazepam administration misdiagnosed as recurrent endozepine stupor
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چکیده
منابع مشابه
Suspected covert lorazepam administration misdiagnosed as recurrent endozepine stupor.
We recently reported in Brain (Lugaresi et al., 1998) 20 cases of idiopathic recurrent stupor due to endozepine-4 accumulation in the blood. Samples obtained from nine of these patients were analysed by gas chromatography–mass spectrometry to rule out contaminating synthetic benzodiazepines (Rothstein et al., 1992). All these samples contained endozepine-4 concentrations high enough to account ...
متن کاملEndozepine stupor. Recurring stupor linked to endozepine-4 accumulation.
Recurring stupor can be caused by repeated metabolic, toxic or structural brain disturbances. Recently, cases of recurring stupor, with fast EEG activity were shown to display increased endogenous benzodiazepine-like activity during the episodes of stupor. Patients with recurring stupor underwent extensive metabolic and toxicologic screening, EEG and brain imaging. Endozepines and exogenously a...
متن کاملModafinil in endozepine stupor. A case report.
BACKGROUND Endozepine-4 stupor is a rare disorder. It presents with recurrent episodes of stupor and coma. Endozepine-4 levels are elevated during an attack with electroencephalogram showing fast activity during the ictal phase. There is no specific treatment and various drugs have been tried without long-term benefit. METHOD We used the vigilance promoting drug modafinil to prevent such atta...
متن کاملRecurrent stupor due to lysinuric protein intolerance.
Recurrent stupor in children is an uncommon clinical problem with a wide differential diagnosis; inherited metabolic disorders account for a vast majority. We report a 9-year-old girl with recurrent episodes of stupor. Initial episode was treated as viral encephalitis and the second episode was managed as non-convulsive status epilepticus. Hyperammonemia was detected in the last episode. Metabo...
متن کاملIdiopathic recurrent stupor mimicking status epilepticus.
Stupor is defined as a deep sleep or behaviourally similar unresponsiveness from which the subject can be aroused only by vigorous repeated stimuli. Causes of stupor may be related to brain damage, toxic or metabolic encephalopathies. Idiopathic recurring stupor is a stupurous condition of unknown aetiology, unrelated to structural, toxic or metabolic disturbance. This condition responds to flu...
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ژورنال
عنوان ژورنال: Brain
سال: 1998
ISSN: 1460-2156
DOI: 10.1093/brain/121.11.2201